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Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

Authors :
Wei-Yu Lin
Sarah E. Fordham
Eric Hungate
Nicola J. Sunter
Claire Elstob
Yaobo Xu
Catherine Park
Anne Quante
Konstantin Strauch
Christian Gieger
Andrew Skol
Thahira Rahman
Lara Sucheston-Campbell
Junke Wang
Theresa Hahn
Alyssa I. Clay-Gilmour
Gail L. Jones
Helen J. Marr
Graham H. Jackson
Tobias Menne
Mathew Collin
Adam Ivey
Robert K. Hills
Alan K. Burnett
Nigel H. Russell
Jude Fitzgibbon
Richard A. Larson
Michelle M. Le Beau
Wendy Stock
Olaf Heidenreich
Abrar Alharbi
David J. Allsup
Richard S. Houlston
Jean Norden
Anne M. Dickinson
Elisabeth Douglas
Clare Lendrem
Ann K. Daly
Louise Palm
Kim Piechocki
Sally Jeffries
Martin Bornhäuser
Christoph Röllig
Heidi Altmann
Leo Ruhnke
Desiree Kunadt
Lisa Wagenführ
Heather J. Cordell
Rebecca Darlay
Mette K. Andersen
Maria C. Fontana
Giovanni Martinelli
Giovani Marconi
Miguel A. Sanz
José Cervera
Inés Gómez-Seguí
Thomas Cluzeau
Chimène Moreilhon
Sophie Raynaud
Heinz Sill
Maria Teresa Voso
Francesco Lo-Coco
Hervé Dombret
Meyling Cheok
Claude Preudhomme
Rosemary E. Gale
David Linch
Julia Gaal-Wesinger
Andras Masszi
Daniel Nowak
Wolf-Karsten Hofmann
Amanda Gilkes
Kimmo Porkka
Jelena D. Milosevic Feenstra
Robert Kralovics
David Grimwade
Manja Meggendorfer
Torsten Haferlach
Szilvia Krizsán
Csaba Bödör
Friedrich Stölzel
Kenan Onel
James M. Allan
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Genome wide association studies in cancer are used to understand the heritable genetic contribution to disease risk. Here, the authors perform a genome wide association study in European patients with acute myeloid leukemia and identify loci associated with risk of developing the disease.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.b98174c0ab9448b282785b148dd6b082
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-26551-x