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Studies on the Binding of DNA with the Inclusion of Brilliant Green inside the Cavity of γ-Cyclodextrin
- Source :
- Iranian Journal of Chemistry & Chemical Engineering, Vol 32, Iss 2, Pp 41-47 (2013)
- Publication Year :
- 2013
- Publisher :
- Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR, 2013.
-
Abstract
- The interaction of brilliant green with herring sperm DNA was investigated in detail by spectrometric methods in γ-cyclodextrin systems. On the condition of physiological pH, brilliant green prefers to form the 1:1 inclusion complex with γ-cyclodextrin.All the evidences indicated that the binding modes between γ-cyclodextrin-brilliant green and DNA were grooving binding and partial non-classical intercalative binding. The binding ratio of the inclusion complex with DNA is 6:1. The calculated thermodynamic parameters suggested that the binding of the inclusion complex to DNA was driven mainly by entropy.
Details
- Language :
- English
- ISSN :
- 10219986
- Volume :
- 32
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- Iranian Journal of Chemistry & Chemical Engineering
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.b98c77fdb292479193ebce0bf5f0feeb
- Document Type :
- article