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Assessing Treatment Efficacy and Determinants of Outcome in Isoniazid Mono-resistant Tuberculosis Patients: A Prospective Observational Study in Gujarat
- Source :
- Acta Medica International, Vol 11, Iss 1, Pp 15-19 (2024)
- Publication Year :
- 2024
- Publisher :
- Wolters Kluwer Medknow Publications, 2024.
-
Abstract
- Introduction: There is a high number of isoniazid-resistant tuberculosis (TB) in India; estimates imply that over 25% of TB patients there are isoniazid-resistant. Hence, the study aimed to evaluate the effectiveness of therapy for patients with isoniazid-mono-resistant TB and the negative effects of the H-mono-resistant TB Regime. Materials and Methods: It was a hospital-based prospective observational study from September 2021 to August 2022. Hence, 100 patients diagnosed with isoniazid mono-resistance TB enrolled in this study. After obtaining the prior informed consent of all patients willing to approve the collection and publication of their data, including extensive clinical history and radiological, microbiological, and biochemical investigations, this study included all diagnosed cases of isoniazid mono-resistant TB. A descriptive statistical analysis was done for continuous and categorical variables. Differences in characteristics between participants were tested with logistic regression and cross-tabulation. P
- Subjects :
- adverse effects, h-mono-resistance, risk factors, treatment outcome
Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 23490578 and 23490896
- Volume :
- 11
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Acta Medica International
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.bb4b554e1b274d178efddc7aaecd4005
- Document Type :
- article
- Full Text :
- https://doi.org/10.4103/amit.amit_91_23