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Investigation into the Antioxidant Activity of Standardized Plant Extracts with Pharmaceutical Potential

Authors :
Elena Moroșan
Magdalena Mititelu
Doina Drăgănescu
Dumitru Lupuliasa
Emma Adriana Ozon
Oana Karampelas
Cerasela Elena Gîrd
Corina Aramă
Marilena Viorica Hovaneț
Adina Magdalena Musuc
Ana Corina Ioniță
Source :
Applied Sciences, Vol 11, Iss 18, p 8685 (2021)
Publication Year :
2021
Publisher :
MDPI AG, 2021.

Abstract

Given the important role of antioxidants in the cellular degeneration process, as well as the increased interest in recent years related to the use of natural antioxidants in therapy, the present study aims to investigate the antioxidant activity of a new pharmaceutical product containing natural antioxidants extracted from plant raw materials. In a first step, the product conventionally named “CILTAG”, containing a mixture in equal proportions of 10% hydroalcoholic extractive solutions of dried plant raw materials from Medicaginis herba, Trifolii pratense flores, Ginkgo bilobae folium, Myrtilli fructus, and Cynosbati fructus, was obtained. In the second stage, the antioxidant activity of the hydroalcoholic extractive solutions included in the pharmaceutical product was tested by chemiluminescence and electrochemical methods and by the superoxide dismutase (SOD) method. The electrochemical determination of the antioxidant capacity of hydroalcoholic extractive solutions was based on a method that provides an indirect evaluation of the presumed antioxidant properties of some compounds using Trolox (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid), as a standard measurement. The experimental results indicate a significant antioxidant potential for both the analyzed plant extractive solutions that are part of CILTAG and the final product.

Details

Language :
English
ISSN :
11188685 and 20763417
Volume :
11
Issue :
18
Database :
Directory of Open Access Journals
Journal :
Applied Sciences
Publication Type :
Academic Journal
Accession number :
edsdoj.bb9a110632146a5950b31ba7986ffd1
Document Type :
article
Full Text :
https://doi.org/10.3390/app11188685