Clinical severity of SARS-CoV-2 Omicron BA.4 and BA.5 lineages compared to BA.1 and Delta in South Africa

Authors :: Nicole Wolter
Waasila Jassat
Sibongile Walaza
Richard Welch
Harry Moultrie
Michelle J. Groome
Daniel Gyamfi Amoako
Josie Everatt
Jinal N. Bhiman
Cathrine Scheepers
Naume Tebeila
Nicola Chiwandire
Mignon du Plessis
Nevashan Govender
Arshad Ismail
Allison Glass
Koleka Mlisana
Wendy Stevens
Florette K. Treurnicht
Kathleen Subramoney
Zinhle Makatini
Nei-yuan Hsiao
Raveen Parboosing
Jeannette Wadula
Hannah Hussey
Mary-Ann Davies
Andrew Boulle
Anne von Gottberg
Cheryl Cohen
Source :: Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Publication Year :: 2022
Publisher :: Nature Portfolio, 2022.
Abstract: South Africa experienced a resurgence in COVID-19 in 2022 driven by Omicron subvariants BA.4 and BA.5. Here, the authors investigate the severity of infections caused by these subvariants, and find no difference in the risk of severe outcomes when compared to Omicron BA.1, whilst all Omicron subvariants were less severe than Delta.

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