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Two patients with new granulomatous lung lesions during treatment of Crohn's disease

Two patients with new granulomatous lung lesions during treatment of Crohn's disease

Authors :
Satoshi Takeda
Takanori Akagi
Hiroyuki Miyazaki
Masaru Kodama
Satoshi Yamamoto
Takahiro Beppu
Takashi Nagahama
Toshiyuki Matsui
Kentaro Watanabe
Nobuhiko Nagata
Source :
Respiratory Medicine Case Reports, Vol 12, Iss C, Pp 16-18 (2014)
Publication Year :
2014
Publisher :
Elsevier, 2014.

Abstract

Two patients with granulomatous lung lesions thought to be related to Crohn's disease (CD) are reported. Patient 1 was a 43-year-old man who was diagnosed with CD at age 11 years. He developed a fever in the 38 °C, and a chest X-ray and CT scan showed infiltrates with air bronchograms in the right upper lobe and left lingular segment. Transbronchial lung biopsy (TBLB) revealed granulomatous lesions. Patient 2 was a 76-year-old woman who was diagnosed with CD at age 44 years. Chest CT showed infiltrates and nodular shadows in both lung fields. Video-assisted thoracoscopic surgery (VATS) in June 2012 revealed granulomatous lesions. Tuberculosis, fungal infections, drug-induced lung disorder, and sarcoidosis were ruled out as a cause of the granulomatous lesions in both patients. The aetiology was thought to be CD.

Details

Language :
English
ISSN :
22130071
Volume :
12
Issue :
C
Database :
Directory of Open Access Journals
Journal :
Respiratory Medicine Case Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.bbece6a2eefa4912b60f717767d297b2
Document Type :
article
Full Text :
https://doi.org/10.1016/j.rmcr.2014.02.002