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Epidemiological Investigation of Goose Astrovirus in Hebei Province, China, 2019–2021

Authors :
Ligong Chen
Huan Cui
Jiaqi Li
Yuxin Zhang
Heng Wang
Yejin Yang
Xuejing Wang
Cheng Zhang
Juxiang Liu
Source :
Microorganisms, Vol 12, Iss 5, p 990 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

The goose astrovirus (GAstV), a key pathogen causing visceral gout and high mortality in geese, has spread widely in China, with frequent outbreaks in recent years. Outbreaks and transmissions of this virus have been reported across China, causing considerable economic losses to the goose industry worldwide, with losses exceeding tens of billions in China alone. However, there is still no effective prevention strategy against this virus. Therefore, continuous monitoring of the genetic diversity of dominant GAstV strains is crucial for developing targeted vaccines and appropriate therapeutics. As a crucial region for goose breeding in China, Hebei Province has previously lacked reports on the epidemiology of GAstV. Hence, investigating the epidemiology of GAstV in Hebei Province is highly important. From January 2019 to December 2021, 474 samples suspected of having a GAstV infection were collected in Hebei Province in this study. Through detailed histological observations, pathological examinations, virus isolation and identification, and genetic diversity analysis, we found that GAstV-2 has become the predominant circulating genotype. However, the presence of GAstV-1 and mixed infections cannot be ignored and should receive increased attention. The findings of this study not only deepened our understanding of GAstV in waterfowl in China but also provided scientific evidence for developing effective prevention and control measures, thereby promoting the healthy development of the goose industry in China.

Details

Language :
English
ISSN :
20762607
Volume :
12
Issue :
5
Database :
Directory of Open Access Journals
Journal :
Microorganisms
Publication Type :
Academic Journal
Accession number :
edsdoj.bbef66d2dd44233840eaed473019607
Document Type :
article
Full Text :
https://doi.org/10.3390/microorganisms12050990