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MALAT1-dependent hsa_circ_0076611 regulates translation rate in triple-negative breast cancer
- Source :
- Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Portfolio, 2022.
-
Abstract
- The circular isoform of VEGFA mRNA (circ_0076611), associated with size and pathogenesis of triple-negative breast tumors, is produced via back splicing of exon-7 by a RNP complex comprising lncRNA-MALAT1, ID4 and SRSF1, and secreted through exosomes.
- Subjects :
- Biology (General)
QH301-705.5
Subjects
Details
- Language :
- English
- ISSN :
- 23993642
- Volume :
- 5
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Communications Biology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.bc6a072f133f4fc982ec9fc88ab62c07
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s42003-022-03539-x