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Non-Coding RNAs: Novel Regulators of Macrophage Homeostasis in Ocular Vascular Diseases
- Source :
- Biomolecules, Vol 14, Iss 3, p 328 (2024)
- Publication Year :
- 2024
- Publisher :
- MDPI AG, 2024.
-
Abstract
- Ocular neovascularization can impair vision and threaten patients’ quality of life. However, the underlying mechanism is far from transparent. In all mammals, macrophages are a population of cells playing pivotal roles in the innate immune system and the first line of defense against pathogens. Therefore, it has been speculated that the disfunction of macrophage homeostasis is involved in the development of ocular vascular diseases. Moreover, various studies have found that non-coding RNAs (ncRNAs) regulate macrophage homeostasis. This study reviewed past studies of the regulatory roles of ncRNAs in macrophage homeostasis in ocular vascular diseases.
- Subjects :
- non-coding RNA
macrophage
pathological angiogenesis
Microbiology
QR1-502
Subjects
Details
- Language :
- English
- ISSN :
- 2218273X
- Volume :
- 14
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Biomolecules
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.bc7f2d4503d14968b272d72ab13721f9
- Document Type :
- article
- Full Text :
- https://doi.org/10.3390/biom14030328