Back to Search Start Over

Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy

Authors :
Shumei Kato
Ki Hwan Kim
Hyo Jeong Lim
Amelie Boichard
Mina Nikanjam
Elizabeth Weihe
Dennis J. Kuo
Ramez N. Eskander
Aaron Goodman
Natalie Galanina
Paul T. Fanta
Richard B. Schwab
Rebecca Shatsky
Steven C. Plaxe
Andrew Sharabi
Edward Stites
Jacob J. Adashek
Ryosuke Okamura
Suzanna Lee
Scott M. Lippman
Jason K. Sicklick
Razelle Kurzrock
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

A molecular tumor board (MTB) is often used as a platform that integrates clinical and molecular parameters for clinical decision making. Here, the authors review the outcome of 715 cancer patients presented at their institution’s MTB, and demonstrate that patients who received a MTB-recommended regimen received therapy that was better matched to their alterations and achieved better clinical outcomes.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.be2daa0bb1884adbb304041e571d8edf
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-18613-3