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Light-sheet photonic force optical coherence elastography for high-throughput quantitative 3D micromechanical imaging

Authors :
Yuechuan Lin
Nichaluk Leartprapun
Justin C. Luo
Steven G. Adie
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

The authors introduce photonic force optical coherence elastography that uses a light-sheet for parallelised and localised mechanical loading. They demonstrate the combination of 3D imaging of extracellular matrix mechanics with cellular-scale resolution and dynamic monitoring of cell-mediated changes.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723 and 81733755
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.bfd099b6c0cf490bbf817337558adb63
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-30995-0