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Biomolecular condensates formed by designer minimalistic peptides

Authors :
Avigail Baruch Leshem
Sian Sloan-Dennison
Tlalit Massarano
Shavit Ben-David
Duncan Graham
Karen Faulds
Hugo E. Gottlieb
Jordan H. Chill
Ayala Lampel
Source :
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

The molecular mechanisms underlying the formation of biomolecular condensates have not been fully elucidated. Here the authors show that the LLPS propensity, dynamics, and encapsulation efficiency of designed peptide condensates can be tuned by subtle changes to the peptide composition.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f00422fac195453c853a9e060b8a14fb
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-023-36060-8