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Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
- Source :
- Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
- Publication Year :
- 2017
- Publisher :
- Nature Portfolio, 2017.
-
Abstract
- Coxsackievirus A6 (CVA6) causes hand, foot and mouth disease in children. Here the authors present the CVA6 procapsid and A-particle cryo-EM structures and identify an immune-dominant neutralizing epitope, which can be exploited for vaccine development.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 8
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f06de03619794e4cae31c9264a758c1f
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-017-00477-9