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Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform
- Source :
- Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
- Publication Year :
- 2020
- Publisher :
- Nature Portfolio, 2020.
-
Abstract
- Chiuppesi et al. demonstrate the use of a synthetic poxvirus-based platform to rapidly generate multi-antigenic vaccine candidates expressing spike and nucleocapsid antigens of SARS-CoV-2. Immunization of mice stimulates potent antigen-specific humoral and cellular immune responses, including neutralizing antibodies.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 11
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.f0cbf9ed7ce4cb899492b5771e12516
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-020-19819-1