Back to Search Start Over

Oxytocin measurements in saliva: an analytical perspective

Oxytocin measurements in saliva: an analytical perspective

Authors :
Marina López-Arjona
María Botía
Silvia Martínez-Subiela
José Joaquín Cerón
Source :
BMC Veterinary Research, Vol 19, Iss 1, Pp 1-11 (2023)
Publication Year :
2023
Publisher :
BMC, 2023.

Abstract

Abstract Oxytocin has traditionally been known for its physiological effects on muscle contraction associated with birth and lactation, but in the last years is widely used as a biomarker of “positive experiences” in psychology and behavior. Different types of samples have been used for oxytocin measurements with saliva samples having the particular advantage of an easy and non-stressful collection. However, the low concentration of oxytocin in saliva can represent a limitation for its use. For this reason, sensitive assays and even a previous sample treatment in some cases are required for saliva oxytocin quantification. In addition, the lack of standardized and generally agreed-upon approach to peripheral oxytocin measurement leads to large discrepancies between different laboratories, that use different sample treatment protocols and different assays. The main objectives of this review are to describe the current status of the use of saliva for oxytocin measurement, provide details of the different sample processing techniques that can be applied and inform about the analytical techniques and assays available in different animal species, and also in humans for comparative purposes. It is expected that this information can contribute to an increase in the knowledge about the measurements of oxytocin in saliva and to its wider use in the future.

Details

Language :
English
ISSN :
17466148
Volume :
19
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Veterinary Research
Publication Type :
Academic Journal
Accession number :
edsdoj.f0f2640d59f644e086ad92455aab2199
Document Type :
article
Full Text :
https://doi.org/10.1186/s12917-023-03661-w