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Use of trifluoroacetaldehyde N-tfsylhydrazone as a trifluorodiazoethane surrogate and its synthetic applications

Authors :
Xinyu Zhang
Zhaohong Liu
Xiangyu Yang
Yuanqing Dong
Matteo Virelli
Giuseppe Zanoni
Edward A. Anderson
Xihe Bi
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Since fluoro-compounds are popular in industrial settings, efficient methods for incorporation of fluoride into organic molecules are desirable. Here, the authors developed trifluoroacetaldehyde N-tfsylhydrazone (TFHZ-Tfs) as a CF3CHN2 surrogate that generates CF3CHN2 in situ under basic conditions.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f16d80073b9e4ad596a828624a933cc7
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-08253-z