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Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy

Authors :
Inka Negwer
Andreas Best
Meike Schinnerer
Olga Schäfer
Leon Capeloa
Manfred Wagner
Manfred Schmidt
Volker Mailänder
Mark Helm
Matthias Barz
Hans-Jürgen Butt
Kaloian Koynov
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

While nanocarrier-based drug delivery is a promising therapeutic approach, in situ characterization of drug nanocarriers in blood remains difficult. Here, the authors demonstrate how the fluorescence correlation spectroscopy can be used to directly characterize drug nanocarriers in flowing blood.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f29261ca73b441fab35b8f08719a659
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-07755-0