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New insights into fibrous cap thickness of vulnerable plaques assessed by optical coherence tomography

Authors :
Xianglan Liu
Wujian He
Xulin Hong
Duanbin Li
Zhezhe Chen
Yao Wang
Zhaoyang Chen
Yi Luan
Wenbin Zhang
Source :
BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-8 (2022)
Publication Year :
2022
Publisher :
BMC, 2022.

Abstract

Abstract Objective Vulnerable plaques with fibrous cap thickness (FCT) of ≤65 μm are prone to rupture and/or thrombosis. However, plaques with FCT > 65 μm cause acute myocardial infarction and even sudden death. We aimed to investigate the relationship between 65 80 μm, n = 271). Clinical and laboratory data was collected from the inpatient medical record system. Results Plaques with thinner FCT, especially 80 μm (P 80 μm]: OR = 8.082, 95% CI = 4.861 to 13.435, P 80 μm]: OR = 2.463, 95% CI = 1.370 to 4.430, P = 0.003), thrombosis ([FCT ≤ 65 μm vs. FCT > 80 μm]: OR = 25.224, 95% CI = 13.768 to 46.212, P 80 μm]: OR = 3.675, 95% CI = 2.065 to 6.542, P 80 μm]: OR = 22.593, 95% CI = 11.426 to 44.674, P 80 μm]: OR = 4.143, 95% CI = 1.869 to 9.184, P 80 μm.

Details

Language :
English
ISSN :
14712261
Volume :
22
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Cardiovascular Disorders
Publication Type :
Academic Journal
Accession number :
edsdoj.f498ed8bf5446bc80892f36996072bd
Document Type :
article
Full Text :
https://doi.org/10.1186/s12872-022-02896-z