Uncontrolled Asthma: Unmet Needs in the Management of Patients

Marco Caminati,1 Rachele Vaia,1 Fabiana Furci,2 Gabriella Guarnieri,3 Gianenrico Senna1,2 1Department of Medicine, University of Verona, Verona, Italy; 2Allergy Unit and Asthma Center, University of Verona and Verona University Hospital, Verona, Italy; 3Respiratory Pathophysiology Unit, Department of Cardiological, Thoracic and Vascular Sciences, University of Padua, Padua, ItalyCorrespondence: Marco CaminatiDepartment of Medicine, University of Verona and Verona University Hospital, Piazzala L.A. Scuro 10, Verona, 37134, ItalyEmail marco.caminati@univr.itAbstract: The recent scientific research has provided clinicians with the tools for substantially upgrading the standard of care in the field of bronchial asthma. Nevertheless, satisfactory asthma control still remains an unmet need worldwide. Identifying the major determinants of poor control in different asthma severity levels represents the first step towards the improvement of the overall patients’ management. The present review aims to provide an overview of the main unmet needs in asthma control and of the potential tools for overcoming the issue. Implementing a personalized medicine approach is essential, not only in terms of pharmacological treatments, biologic drugs or sophisticated biomarkers. In fact, exploring the complex profile of each patient, from his inflammation phenotype to his preferences and expectations, may help in filling the gap between the big potential of currently available treatments and the overall unsatisfactory asthma control. Telemedicine and e-health technologies may provide a strategy to both optimize disease assessment on a regular basis and enhance patients’ empowerment in managing their asthma. Increasing patients’ awareness as well as the physicians’ knowledge about asthma phenotypes and treatment options besides corticosteroid probably represent the key and more difficult goals of all the players involved in asthma management at every level.Keywords: asthma, asthma control, severe asthma, mild to moderate asthma, telemedicine, personalized medicine