The effectiveness of long-term course of Sterimar Mn nasal spray for treatment of the recurrence rates of acute allergic rhinitis in patients with chronic allergic rhinitis

Michele Grasso,1 Marco de Vincentiis,1 Griselda Agolli,1 Francesco Cilurzo,2 Raffaele Grasso2 1ENT Department, Head and Neck Surgery, University “Sapienza”, Rome, Italy; 2ENT Department, Head and Neck Surgery, Lamezia Terme Hospital, Calabria, Italy Background: The “cost of illness” of the acute allergic rhinitis (AR) episodes in patients with chronic AR is very high in terms of therapy and quality of life. AR represents a worldwide health problem; despite the fact that many standardized treatments have been proposed and used, the recurrence rate of acute rhinitis episodes in springtime is always higher.Materials and methods: Sixty consecutive patients (13 F and 17 M in group A, 15 F and 15 M in group B; p=0.60) with chronic AR were enrolled in this prospective, controlled clinical trial. Thirty patients were treated daily for the same 5 months of the following year (2013) with isotonic seawater nasal spray enriched with manganese (Sterimar Mn; 4 puffs/day), whereas 30 patients received only the standard care and were used as control group.Results: A 5 months course treatment with the nasal Sterimar Mn was able to decrease, significantly (p