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Differential Placental DNA Methylation of NR3C1 in Extremely Preterm Infants With Poorer Neurological Functioning

Authors :
Nienke H. van Dokkum
Sofia Bachini
Rikst Nynke Verkaik-Schakel
Dyvonne H. Baptist
Sahar Salavati
Karianne E. Kraft
Sicco A. Scherjon
Arend F. Bos
Torsten Plösch
Source :
Frontiers in Pediatrics, Vol 10 (2022)
Publication Year :
2022
Publisher :
Frontiers Media S.A., 2022.

Abstract

BackgroundUnderstanding underlying mechanisms of neurodevelopmental impairment following preterm birth may enhance opportunities for targeted interventions. We aimed to assess whether placental DNA methylation of selected genes affected early neurological functioning in preterm infants.MethodsWe included 43 infants, with gestational age

Details

Language :
English
ISSN :
22962360
Volume :
10
Database :
Directory of Open Access Journals
Journal :
Frontiers in Pediatrics
Publication Type :
Academic Journal
Accession number :
edsdoj.f610238192dd461995ca97291e507900
Document Type :
article
Full Text :
https://doi.org/10.3389/fped.2022.876803