Non⁃invasive evaluation of intracranial pressure by transcranial Doppler ultrasound in patients with traumatic brain injury

Objective To investigate the non⁃invasive evaluation of intracranial pressure (ICP) by transcranial Doppler ultrasound (TCD) in patients with traumatic brain injury (TBI). Methods The clinical data of 68 patients with TBI were retrospectively analyzed. Pulsatility index (PI) and optic nerve sheath diameter (ONSD) were performed by TCD, simultaneous recording of ICP parameter one week after surgery. The relationship between ONSD, PI and ICP was analyzed by Pearson correlation analysis. The area under the curve (AUC) was used to evaluate the diagnostic sensitivity of ONSD and PI for prediction intracranial hypertension. Results One week after surgery,ICP was positively correlated with ONSD (r= 0.679, P=0.000). There was also a positive correlation between ONSD and ICP ≥ 20 mm Hg (r=0.665, P= 0.000) and ICP