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Low Seroprevalence of Aichi Virus Infection in Taiwan

Authors :
Bao-Chen Chen
Tsi-Shu Huang
Nuan-Ya Huang
Chiao-Shan Chen
Yao-Shen Chen
Tsung-Hsien Chang
Source :
Pathogens, Vol 10, Iss 5, p 553 (2021)
Publication Year :
2021
Publisher :
MDPI AG, 2021.

Abstract

Aichi virus (AiV) belongs to the genus Kobuvirus of the family Picornaviridae; it is a single-stranded positive-sense RNA virus without an envelope. AiV causes acute gastroenteritis, abdominal pain, nausea, vomiting, and fever. Low incidence and high seroprevalence of AiV infections have been reported in several regions of the world; however, little was known on the prevalence of AiV infections in Taiwan. This study described the first two cases of AiV infection and analyzed AiV seroprevalence in Taiwan. A total of 700 sera were collected from a single hospital in southern Taiwan. The neutralization assay was employed to assess AiV neutralization antibodies in the serum. The test identified 48 positive cases, with a seroprevalence of 6.86%. Results also showed a gradual increase in AiV seroprevalence rate with age. Compared with other countries, Taiwan had a relatively low AiV seroprevalence, suggesting a low incidence of or sporadic AiV infections.

Details

Language :
English
ISSN :
20760817
Volume :
10
Issue :
5
Database :
Directory of Open Access Journals
Journal :
Pathogens
Publication Type :
Academic Journal
Accession number :
edsdoj.f81ce1a110a84002ae24931f22458c18
Document Type :
article
Full Text :
https://doi.org/10.3390/pathogens10050553