Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma

Authors :: Nikhil Rabade
Asma Bibi
Kiran Ghodke
Nikhil Patkar
Prashant Tembhare
Pratibha Amare
P G Subramanian
Sumeet Gujral
Source :: Indian Journal of Pathology and Microbiology, Vol 59, Iss 3, Pp 410-412 (2016)
Publication Year :: 2016
Publisher :: Wolters Kluwer Medknow Publications, 2016.
Abstract: Surface light chain expression is a feature of mature B-cell neoplasms. Light chain restriction in precursor B acute lymphoblastic leukemia is infrequently seen. We report a case of a 28-year-old female with non-FAB L3 morphology blasts and immunophenotypic features showing overlap between a precursor and mature B-cell neoplasm.

Subjects :: Burkitt
leukemia
light chain restriction
Pathology
RB1-214
Microbiology
QR1-502

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