Massive expression of cysteine-containing proteins causes abnormal elongation of yeast cells by perturbing the proteasome

AbstractThe enhanced green fluorescent protein (EGFP) is considered to be a harmless protein because the critical expression level that causes growth defects is higher than that of other proteins. Here, we found that overexpression of EGFP, but not a glycolytic protein Gpm1, triggered the cell elongation phenotype in the budding yeast Saccharomyces cerevisiaeSchizosaccharomyces pombeSHOTA