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Multimodal in vivo recording using transparent graphene microelectrodes illuminates spatiotemporal seizure dynamics at the microscale

Authors :
Nicolette Driscoll
Richard E. Rosch
Brendan B. Murphy
Arian Ashourvan
Ramya Vishnubhotla
Olivia O. Dickens
A. T. Charlie Johnson
Kathryn A. Davis
Brian Litt
Danielle S. Bassett
Hajime Takano
Flavia Vitale
Source :
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Driscoll, Rosch et al. design transparent graphene-based surface probes to achieve simultaneous electrophysiological recording and calcium imaging of epileptic seizures in mice. This method could be used to investigate circuit dynamics during seizure onset and evolution with high temporal and spatial resolution.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
4
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.f932d6cf433744e78a90d1a0559256c2
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-021-01670-9