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Viral rhodopsins 1 are an unique family of light-gated cation channels

Authors :
Dmitrii Zabelskii
Alexey Alekseev
Kirill Kovalev
Vladan Rankovic
Taras Balandin
Dmytro Soloviov
Dmitry Bratanov
Ekaterina Savelyeva
Elizaveta Podolyak
Dmytro Volkov
Svetlana Vaganova
Roman Astashkin
Igor Chizhov
Natalia Yutin
Maksim Rulev
Alexander Popov
Ana-Sofia Eria-Oliveira
Tatiana Rokitskaya
Thomas Mager
Yuri Antonenko
Riccardo Rosselli
Grigoriy Armeev
Konstantin Shaitan
Michel Vivaudou
Georg Büldt
Andrey Rogachev
Francisco Rodriguez-Valera
Mikhail Kirpichnikov
Tobias Moser
Andreas Offenhäusser
Dieter Willbold
Eugene Koonin
Ernst Bamberg
Valentin Gordeliy
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Nucleocytoplasmic Large DNA Viruses (NCLDV) that infect algae encode two distinct families of microbial rhodopsins. Here, the authors characterise two proteins form the viral rhodopsin group 1 OLPVR1 and VirChR1, present the 1.4 Å crystal structure of OLPVR1 and show that viral rhodopsins 1 are light-gated cation channels.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.f981896af7bb43078f390f8fc77a17db
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-19457-7