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The regulatory impact of RNA-binding proteins on microRNA targeting

Authors :
Sukjun Kim
Soyoung Kim
Hee Ryung Chang
Doyeon Kim
Junehee Park
Narae Son
Joori Park
Minhyuk Yoon
Gwangung Chae
Young-Kook Kim
V. Narry Kim
Yoon Ki Kim
Jin-Wu Nam
Chanseok Shin
Daehyun Baek
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

miRNAs are loaded into Argonaute protein and repress complementary mRNA targets. Here the authors show the unappreciated role of RNA binding proteins for efficient miRNA targeting and expand the current understanding of miRNA targeting.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.fa80ba4bd3e24c5eae00608527853f85
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-25078-5