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Gold nanoparticles and gold nanorods in the landscape of cancer therapy

Authors :
Prashant Kesharwani
Ruiyang Ma
Liang Sang
Mahak Fatima
Afsana Sheikh
Mohammed A. S. Abourehab
Neelima Gupta
Zhe-Sheng Chen
Yun Zhou
Source :
Molecular Cancer, Vol 22, Iss 1, Pp 1-31 (2023)
Publication Year :
2023
Publisher :
BMC, 2023.

Abstract

Abstract Cancer is a grievous disease whose treatment requires a more efficient, non-invasive therapy, associated with minimal side effects. Gold nanoparticles possessing greatly impressive optical properties have been a forerunner in bioengineered cancer therapy. This theranostic system has gained immense popularity and finds its application in the field of molecular detection, biological imaging, cancer cell targeting, etc. The photothermal property of nanoparticles, especially of gold nanorods, causes absorption of the light incident by the light source, and transforms it into heat, resulting in tumor cell destruction. This review describes the different optical features of gold nanoparticles and summarizes the advance research done for the application of gold nanoparticles and precisely gold nanorods for combating various cancers including breast, lung, colon, oral, prostate, and pancreatic cancer.

Details

Language :
English
ISSN :
14764598
Volume :
22
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Molecular Cancer
Publication Type :
Academic Journal
Accession number :
edsdoj.fab52671a64b4f919e19e151ee4ec6
Document Type :
article
Full Text :
https://doi.org/10.1186/s12943-023-01798-8