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Research progress on the role of vitamin D supplementation in adjuvant therapy for COVID-19
- Source :
- Xin yixue, Vol 53, Iss 12, Pp 878-881 (2022)
- Publication Year :
- 2022
- Publisher :
- Editorial Office of Journal of New Medicine, 2022.
-
Abstract
- The pandemic caused by coronavirus disease of 2019 (COVID-19) has brought severe challenges to public health all over the world. Vitamin D plays an important role in immune regulation and anti-respiratory virus infection as an immune enhancer. Several studies have demonstrated that vitamin D can regulate the angiotensin-converting enzyme 2/angiotensin (1-7)/Mas receptor axis signaling pathway, inhibit the over-activation of renin-angiotensin system signal, fight against SARS-CoV-2 infection and suppress the production of inflammatory cytokine storm, thereby reducing the risk of pneumonia infection and improving acute respiratory distress syndrome, cardiogenic obstruction and thrombosis in COVID-19 patients. In this article, the mechanism of vitamin D in reducing the risk of SARS-CoV-2 infection and mitigating clinical symptoms was reviewed. It is hypothesized that vitamin D plays a critical role in the prevention or adjuvant therapy for novel coronavirus pneumonia and alleviating clinical manifestations in COVID-19 patients.
- Subjects :
- sars-cov-2
covid-19
vitamin d
cytokine storm
pneumonia
Medicine
Subjects
Details
- Language :
- Chinese
- ISSN :
- 02539802
- Volume :
- 53
- Issue :
- 12
- Database :
- Directory of Open Access Journals
- Journal :
- Xin yixue
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.fb7e65f9752a428eb879b8558cb47550
- Document Type :
- article
- Full Text :
- https://doi.org/10.3969/j.issn.0253-9802.2022.12.003