Metabolic syndrome and thyroid Cancer: risk, prognosis, and mechanism

Highlights Met S and its components were associated with an increased risk and aggressiveness of thyroid cancer. The obese males have a tighter association with thyroid cancer, and females have a higher thyroid cancer risk among diabetes. Thyroid-stimulating hormones may be a switch for thyroid carcinogenesis. Insulin resistance plays a critical role in the development of thyroid cancer. Abnormal levels of adipocytokines and blood pressure related regulatory hormone assist in accelerating thyroid cancer progression.