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Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease
- Source :
- Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
- Publication Year :
- 2019
- Publisher :
- Nature Portfolio, 2019.
-
Abstract
- Multiple myeloma is a cancer of the bone marrow that can induce bone disease. Here, the authors profile the transcriptome of bone-lining cells and find a targetable role of bone morphogenetic protein (BMP) signalling in myeloma-induced bone-disease
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723 and 87742128
- Volume :
- 10
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.fce39d2e8774212826676e3142ffc40
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-019-12296-1