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A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome

Authors :
Perrine Soret
Christelle Le Dantec
Emiko Desvaux
Nathan Foulquier
Bastien Chassagnol
Sandra Hubert
Christophe Jamin
Guillermo Barturen
Guillaume Desachy
Valérie Devauchelle-Pensec
Cheïma Boudjeniba
Divi Cornec
Alain Saraux
Sandrine Jousse-Joulin
Nuria Barbarroja
Ignasi Rodríguez-Pintó
Ellen De Langhe
Lorenzo Beretta
Carlo Chizzolini
László Kovács
Torsten Witte
PRECISESADS Clinical Consortium
PRECISESADS Flow Cytometry Consortium
Eléonore Bettacchioli
Anne Buttgereit
Zuzanna Makowska
Ralf Lesche
Maria Orietta Borghi
Javier Martin
Sophie Courtade-Gaiani
Laura Xuereb
Mickaël Guedj
Philippe Moingeon
Marta E. Alarcón-Riquelme
Laurence Laigle
Jacques-Olivier Pers
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Sjögren’s syndrome, a disease that primarily affects women, is poorly understood. Here, the authors combine data from a large cohort of patients and healthy controls to identify biomarkers that distinguish patient subgroups to improve our understanding of the disease and facilitate drug development.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.fd749685034f43a3afc45a40aaefddd7
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-23472-7