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Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium.

Authors :
Megan L Grove
Bing Yu
Barbara J Cochran
Talin Haritunians
Joshua C Bis
Kent D Taylor
Mark Hansen
Ingrid B Borecki
L Adrienne Cupples
Myriam Fornage
Vilmundur Gudnason
Tamara B Harris
Sekar Kathiresan
Robert Kraaij
Lenore J Launer
Daniel Levy
Yongmei Liu
Thomas Mosley
Gina M Peloso
Bruce M Psaty
Stephen S Rich
Fernando Rivadeneira
David S Siscovick
Albert V Smith
Andre Uitterlinden
Cornelia M van Duijn
James G Wilson
Christopher J O'Donnell
Jerome I Rotter
Eric Boerwinkle
Source :
PLoS ONE, Vol 8, Iss 7, p e68095 (2013)
Publication Year :
2013
Publisher :
Public Library of Science (PLoS), 2013.

Abstract

Genotyping arrays are a cost effective approach when typing previously-identified genetic polymorphisms in large numbers of samples. One limitation of genotyping arrays with rare variants (e.g., minor allele frequency [MAF]

Subjects

Subjects :
Medicine
Science

Details

Language :
English
ISSN :
19326203
Volume :
8
Issue :
7
Database :
Directory of Open Access Journals
Journal :
PLoS ONE
Publication Type :
Academic Journal
Accession number :
edsdoj.fe89b59ec376416c8ad60ee60b330ff5
Document Type :
article
Full Text :
https://doi.org/10.1371/journal.pone.0068095