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The Study in Animal Models of Local Action, Acute and Chronic Toxicity of Inactivated Influenza Vaccine Ultriks in Syringe

Authors :
O. G. Kurskaya
K. A. Sharshov
A. Yu. Alekseev
M. A. Gulyaeva
A. M. Shestopalov
L. V. Shestopalova
G. M. Ignatev
V. A. Shkurupiy
Source :
Эпидемиология и вакцинопрофилактика, Vol 14, Iss 3, Pp 66-73 (2015)
Publication Year :
2015
Publisher :
Numikom LLC, 2015.

Abstract

The evaluation of acute and chronic toxicity and local effect of the inactivated influenza vaccine Ultriks in animal models (guinea pigs, mice BALB/c) was performed. No vaccine-related toxic effect after a single intraperitoneal injection, multiple intramuscular injections, and no local irritant effect after a single intramuscular injection were reported in experimental animals.

Details

Language :
Russian
ISSN :
20733046 and 26190494
Volume :
14
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Эпидемиология и вакцинопрофилактика
Publication Type :
Academic Journal
Accession number :
edsdoj.fef061caff074f39926037dc45526ac3
Document Type :
article
Full Text :
https://doi.org/10.31631/2073-3046-2015-14-3-66-73