A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer’s disease and gastrointestinal tract disorders

Authors :: Emmanuel O. Adewuyi
Eleanor K. O’Brien
Dale R. Nyholt
Tenielle Porter
Simon M. Laws
Source :: Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Publication Year :: 2022
Publisher :: Nature Portfolio, 2022.
Abstract: A cross-trait meta-analysis of several genome-wide association studies suggest that Alzheimer’s disease shares a common genetic basis (including 7 shared loci) and underlying biological pathways with gastrointestinal tract disorders.

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