Can basic magnetic resonance imaging along with neuropsychological assessment be used as a cost-effective means for the detection of early dementia in the Indian sub-continent?

Introduction: The mild cognitive impairment (MCI) stage occurs sporadically between healthy aging and the onset of Alzheimer's disease (AD). MCI shows significant defacement in magnetic resonance imaging (MRI) of the brain along with neuropsychological and behavioral parameters. Aim: Assessment of neuropsychological, behavioral, and structural MRI changes in MCI and their relation with each other. Methodology: Seventy-eight participants in the MCI group and healthy controls (HC) were assessed using Addenbrooke's Cognitive Examination (ACE), Mini-Mental Status Examination (MMSE), Clinical Dementia Rating Scale (CDR); and behavioral assessment by using Behavioral Pathology In AD (BEHAVE-AD). MRI brain volumetric analysis was performed using the software MYRIAN. Statistical analysis was performed using the Mann–Whitney U test, unpaired t-test (P =