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Frontiers in Protein Structure, Function, and Dynamics
- Publication Year :
- 2020
-
Abstract
- This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances. Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecularmotors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins. Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction.
- Subjects :
- Proteins
Enzymology
Medical genetics
Bioinformatics
Subjects
Details
- Language :
- English
- ISBNs :
- 9789811555299 and 9789811555305
- Database :
- eBook Index
- Journal :
- Frontiers in Protein Structure, Function, and Dynamics
- Publication Type :
- eBook
- Accession number :
- 2519800