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Vancomycin-resistant enterococcus infection in the hematopoietic stem cell transplant recipient: an overview of epidemiology, management, and prevention [version 1; referees: 3 approved]

Authors :
Esther Benamu
Stanley Deresinski
Author Affiliations :
<relatesTo>1</relatesTo>Division of Infectious Diseases, Department of Medicine, University of Colorado, Aurora, USA<br /><relatesTo>2</relatesTo>Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, USA
Source :
F1000Research. 7:F1000 Faculty Rev-3
Publication Year :
2018
Publisher :
London, UK: F1000 Research Limited, 2018.

Abstract

Vancomycin-resistant enterococcus (VRE) is now one of the leading causes of nosocomial infections in the United States. Hematopoietic stem cell transplantation (HSCT) recipients are at increased risk of VRE colonization and infection. VRE has emerged as a major cause of bacteremia in this population, raising important clinical questions regarding the role and impact of VRE colonization and infection in HSCT outcomes as well as the optimal means of prevention and treatment. We review here the published literature and scientific advances addressing these thorny issues and provide a rational framework for their approach.

Subjects

Subjects :
Review
Articles
Bacterial Infections
Vancomycin resistant enterococcus
Hematopoietic stem cell transplantation
bacteremia

Details

ISSN :
20461402
Volume :
7
Database :
F1000Research
Journal :
F1000Research
Notes :
Editorial Note on the Review Process F1000 Faculty Reviews are commissioned from members of the prestigious F1000 Faculty and are edited as a service to readers. In order to make these reviews as comprehensive and accessible as possible, the referees provide input before publication and only the final, revised version is published. The referees who approved the final version are listed with their names and affiliations but without their reports on earlier versions (any comments will already have been addressed in the published version). The referees who approved this article are: Jayanta Haldar, Chemical Biology and Medicinal Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre For Advanced Scientific Research, Karnataka, India No competing interests were disclosed. Vincent Cattoir, Department of Clinical Microbiology, Rennes University Hospital, Rennes, France No competing interests were disclosed. Catherine Liu, Vaccine and Infectious Disease Division and Clinical Research Division, Fred Hutchinson Cancer Research Center, Washington, USA; Division of Allergy and Infectious Disease, University of Washington, Washington, USA No competing interests were disclosed. Erica Stohs, Division of Allergy and Infectious Diseases, University of Washington, Washington, USA No competing interests were disclosed., , [version 1; referees: 3 approved]
Publication Type :
Academic Journal
Accession number :
edsfor.10.12688.f1000research.11831.1
Document Type :
review
Full Text :
https://doi.org/10.12688/f1000research.11831.1
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