Assessing the efficacy of hemoglobin electrophoresis as a diagnostic tool in moderate to severe anemia: a study protocol [version 1; peer review: 2 not approved]

Patients with hemoglobinopathy may experience short-term benefits from nutritional support and blood transfusions, but long-term results may be better if a precise diagnosis is obtained and a precise course of treatment or safety measures is adopted. The goal of the study is to determine the prevalence of haemoglobin abnormalities in people who presented with moderate to severe anaemia using haemoglobin electrophoresis They will undergo haemoglobin electrophoresis to test for the presence of any haemoglobin abnormalities. For anaemia classification, the WHO reference range is used. The outcome and quality of life of patients with haemoglobin disorders can be improved when they are properly managed, and since a significant portion of the patients in our study have hemoglobinopathies of varying severity, it would be prudent to conduct investigations to determine the precise cause of anaemia, particularly in rural areas where supportive management remains the mainstay of treatment in most scenarios.