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Advances in the prevention, management, and treatment of community-acquired pneumonia [version 1; referees: 2 approved]

Authors :
Mathias W. Pletz
Gernot G. Rohde
Tobias Welte
Martin Kolditz
Sebastian Ott
Author Affiliations :
<relatesTo>1</relatesTo>Center for Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany<br /><relatesTo>2</relatesTo>Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany<br /><relatesTo>3</relatesTo>Department of Respiratory Medicine, Maastricht University Medical Center, Maastricht, Netherlands<br /><relatesTo>4</relatesTo>Division of Pulmonology, University Hospital Carl Gustav Carus, Dresden, Germany<br /><relatesTo>5</relatesTo>Department of Pulmonary Medicine, Inselspital, University Hospital, Bern, Switzerland
Source :
F1000Research. 5:F1000 Faculty Rev-300
Publication Year :
2016
Publisher :
London, UK: F1000 Research Limited, 2016.

Abstract

Community-acquired pneumonia (CAP) is the infectious disease with the highest number of deaths worldwide. Nevertheless, its importance is often underestimated. Large cohorts of patients with CAP have been established worldwide and improved our knowledge about CAP by far. Therefore, current guidelines are much more evidence-based than ever before. This article discusses recent major studies and concepts on CAP such as the role of biomarkers, appropriate risk stratification to identify patients in need of hospitalisation or intensive care, appropriate empiric antibiotic therapy (including the impact of macrolide combination therapy and antibiotic stewardship), and CAP prevention with novel influenza and pneumococcal vaccines.

Subjects

Subjects :
Review
Articles
Antimicrobials & Drug Resistance
Emergency Medicine
Respiratory Infections
Respiratory Problems in Critical Care
community-acquired pneumonia
Streptococcus pneumoniae
pulmonary infection
CAP

Details

ISSN :
20461402
Volume :
5
Database :
F1000Research
Journal :
F1000Research
Notes :
Editorial Note on the Review Process F1000 Faculty Reviews are commissioned from members of the prestigious F1000 Faculty and are edited as a service to readers. In order to make these reviews as comprehensive and accessible as possible, the referees provide input before publication and only the final, revised version is published. The referees who approved the final version are listed with their names and affiliations but without their reports on earlier versions (any comments will already have been addressed in the published version). The referees who approved this article are: Mats Kalin, Department of Medicine, Karolinska Institute, Stockholm, Sweden No competing interests were disclosed. James D. Chalmers, Scottish Centre for Respiratory Research, University of Dundee, Dundee, UK No competing interests were disclosed., , [version 1; referees: 2 approved]
Publication Type :
Academic Journal
Accession number :
edsfor.10.12688.f1000research.7657.1
Document Type :
review
Full Text :
https://doi.org/10.12688/f1000research.7657.1
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