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Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase

Authors :
Cheung, Wang L.
Ajiro, Kozo
Samejima, Kumiko
Kloc, Malgorzata
Cheung, Peter
Mizzen, Craig A.
Beeser, Alexander
Etkin, Laurence D.
Chernoff, Jonathan
Earnshaw, William C.
Allis, C. David
Source :
Cell. May 16, 2003, Vol. 113 Issue 4, 507-517
Publication Year :
2003

Abstract

Research has been conducted on histone H2B. The authors report that phosphorylation of this histone at serine 14 correlates with cell death in vertebrates, and that apoptosis-induced H2B kinase has been identified as caspase-cleaved mammalian sterile twenty kinase.

Details

Language :
English
ISSN :
00928674
Volume :
113
Issue :
4
Database :
Gale General OneFile
Journal :
Cell
Publication Type :
Academic Journal
Accession number :
edsgcl.102955590