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Sialylation levels influence oligosaccharide quantitation: analyzing response variability using high-pH anion-exchange chromatography and pulsed amperometric detection. (Process Development)

Authors :
Ganesa, Chandrashekar
Granda, Brian W.
Mattaliano, Robert J.
Source :
Biopharm International. June, 2003, Vol. 16 Issue 6, 44
Publication Year :
2003

Abstract

Oligosaccharide structures and the degree of sialylation can cause variability among detection cells when using high-pH anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD) technology for oligosaccharide characterization. That variability can [...]

Details

Language :
English
ISSN :
1542166X
Volume :
16
Issue :
6
Database :
Gale General OneFile
Journal :
Biopharm International
Publication Type :
Periodical
Accession number :
edsgcl.105408204