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Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis
- Source :
- Biochemistry. June 24, 2003, Vol. 42 Issue 24, 7381-7389
- Publication Year :
- 2003
-
Abstract
- Research has been conducted on serpin superfamily member hurpin, linked to human keratinocyte apoptosis. Results deminstrate that hurpin is an inhibitor of the archetypal lysosome cysteine proteinase cathepsin L.
- Subjects :
- Biochemistry -- Research
Lysosomes -- Physiological aspects
Chemical inhibitors -- Physiological aspects
Apoptosis -- Physiological aspects
Cathepsins -- Physiological aspects
Ultraviolet radiation -- Physiological aspects
Keratinocytes -- Physiological aspects
Cysteine -- Physiological aspects
Biological sciences
Chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 00062960
- Volume :
- 42
- Issue :
- 24
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.105969773