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Peripheral binding mode and penetration depth of cobra cardiotoxin on phospholipid membranes as studied by a combined FTIR and computer simulation approch

Authors :
Wei-Ning Huang
Shih-Che Sue
Da-Shin Wang
Po-Long Wu
Wen-guey Wu
Source :
Biochemistry. June 24, 2003, Vol. 42 Issue 24, 7457-7466
Publication Year :
2003

Abstract

Research has been conducted on cobra cardiotoxin which causes membrane leakage in human erythrocytes. The authors report that this cardiotoxin can cause leakage of vesicle contents in phosphatidylglycerol and phosphatidylserine which contain membrane bilayers.

Details

Language :
English
ISSN :
00062960
Volume :
42
Issue :
24
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.105980370