A virus-encoded 'superantigen' in a retrovirus-induced immunodeficiency syndrome of mice

Authors :: Hugin, Ambros W.
Vacchio, Melanie S.
Morse, III, Herbert C.
Source :: Science. April 19, 1991, Vol. 252 Issue 5004, p424, 4 p.
Publication Year :: 1991
Abstract: The development of an immunodeficiency syndrome of mice caused by a replication-defective murine leukemia virus (MuLV) is paradoxically associated with a rapid activation and proliferation of [CD4.sup.+] T cells that [...]

Subjects :: Research
Antigens -- Research
Cell proliferation -- Research
Mouse leukemia viruses -- Research
Immunologic deficiency syndromes -- Research
T cells -- Research
Immunological deficiency syndromes -- Research

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