RZnl vs. [R.sub.2]Zn in Pd(0)-catalyzed cross-coupling reactions with thioimidates

Authors :: Roberts, William P.
Ghosh, Indranath
Jacobi, Peter A.
Source :: Canadian Journal of Chemistry. Feb, 2004, Vol. 82 Issue 2, p279, 6 p.
Publication Year :: 2004
Abstract: Thioimidates 1-Z undergo facile cross-coupling with Pd(0)-RZnI but are inert to Pd(0)-[R.sub.2]Zn. This difference is due to the lower Lewis acidity of [R.sub.2]Zn, as opposed to lower nucleophilicity. Various sources of RZnI (R = Me, Et) and Pd(0) were evaluated for their convenience and reactivity. Key words: thioimidates, cross-coupling, dialkylzincs, alkylzinc iodides.

Subjects :: Organometallic compounds -- Analysis
Palladium catalysts -- Analysis
Chemical reactions -- Analysis

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