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A Glassy carbon microfluidic device for electrospray mass spectrometry
- Source :
- Analytical Chemistry. April 15, 2004, Vol. 76 Issue 8, p2393, 5 p.
- Publication Year :
- 2004
-
Abstract
- Due to the broad impact of microfabrication technology on chemistry and biology, new methods to pattern and etch a variety of materials are being explored in a number of laboratories. Here, we report the design, fabrication, and operation of a glassy carbon (GC) microchip interfaced to a nanoelectrospray ionization source and a quadrupole mass spectrometer. The method involves standard photolithographic pattern transfer to a photoresist layer and anodization of the exposed GC substrate in basic electrolyte to produce a series of channels with well-defined wall structure. The performance of the microchip was evaluated with standard polymer and peptide samples.
- Subjects :
- Chemistry, Analytic -- Research
Chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 00032700
- Volume :
- 76
- Issue :
- 8
- Database :
- Gale General OneFile
- Journal :
- Analytical Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.116931405