Back to Search
Start Over
Diastereoselective 14 beta-hydroxylation of baccatin III derivatives
- Source :
- Journal of Organic Chemistry. Dec 12, 2003, Vol. 68 Issue 25, 9773-9779
- Publication Year :
- 2003
-
Abstract
- The 14-beta hydroxybaccatin III is the starting material for the synthesis of the second-generation anticancer taxoid ortataxel. The 10-deacetylbaccatin III is used to synthesize the 7-tert-butoxycarbonyl, and 7-triethylsilyl derivatives of 14-beta hydroxybaccatin III 1, 14-carbonate.
Details
- Language :
- English
- ISSN :
- 00223263
- Volume :
- 68
- Issue :
- 25
- Database :
- Gale General OneFile
- Journal :
- Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.119174135