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Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis

Authors :
Edwards, Jonathan C.W.
Szczepanski, Leszek
Szechinski, Jacek
Filipowicz-Sosnowska, Anna
Emery, Paul
Close, David R.
Stevens, Randall M.
Shaw, Tim
Source :
The New England Journal of Medicine. June 17, 2004, Vol. 350 Issue 25, p2572, 2581 p.
Publication Year :
2004

Abstract

A randomized, double blind, and controlled study was conducted to confirm the observations of sustained clinical improvements by the use of rituximab for patients with rheumatoid arthritis. The results show that a single course of two infusions of rituximab can improve the disease symptoms.

Details

Language :
English
ISSN :
00284793
Volume :
350
Issue :
25
Database :
Gale General OneFile
Journal :
The New England Journal of Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.120303096